Authors: T. Qassem; D. Aly-ElGabry; A. Alzarouni; K. Abdel-Aziz; Danilo Arnone · Research
How Common Are Other Mental Health Conditions in People with PTSD?
A study of the English population finds that nearly 80% of people with PTSD also have other mental health conditions, most commonly depression.
Source: Qassem, T., Aly-ElGabry, D., Alzarouni, A., Abdel-Aziz, K., & Arnone, D. (2021). Psychiatric Co-Morbidities in Post-Traumatic Stress Disorder: Detailed Findings from the Adult Psychiatric Morbidity Survey in the English Population. Psychiatric Quarterly, 92, 321-330. https://doi.org/10.1007/s11126-020-09797-4
What you need to know
Nearly 80% of people with post-traumatic stress disorder (PTSD) also have at least one other mental health condition.
Depression is the most common co-occurring condition, affecting over half of people with PTSD in severe cases.
Other frequent co-occurring conditions include social anxiety, psychotic symptoms, obsessive-compulsive disorder, and substance use disorders.
Understanding these patterns of co-occurring conditions is important for proper diagnosis and treatment of PTSD.
Understanding PTSD and co-occurring conditions
Post-traumatic stress disorder (PTSD) is a mental health condition that can develop after experiencing or witnessing a traumatic event. While PTSD itself can be very distressing, researchers have found that most people with PTSD also struggle with other mental health conditions at the same time. These additional conditions are called “comorbidities” or “co-occurring conditions.”
To better understand how common these co-occurring conditions are, researchers analyzed data from a large survey of mental health in the English population. They found that nearly 80% of people who met criteria for PTSD also had at least one other mental health diagnosis. This is much higher than the rate of mental health conditions in people without PTSD, which was around 15%.
Understanding these patterns of co-occurring conditions is important for several reasons. First, it can help doctors and therapists provide more comprehensive care by addressing all of a person’s mental health needs, not just PTSD symptoms. Additionally, the presence of other conditions can impact how PTSD manifests and responds to treatment. Finally, recognizing common combinations of symptoms can aid in proper diagnosis, as there is often overlap between PTSD and other conditions.
Depression and PTSD frequently occur together
The study found that depression was the most common co-occurring condition in people with PTSD. Over half of those with severe PTSD also met criteria for severe depression. Even in milder cases, rates of depression were much higher in those with PTSD compared to the general population.
There are several possible explanations for why depression and PTSD so frequently occur together:
The trauma that led to PTSD may also trigger depression.
Ongoing PTSD symptoms like sleep problems, isolation, and negative thoughts may contribute to developing depression.
Depression may make people more vulnerable to developing PTSD after trauma.
There may be shared risk factors or neurobiological mechanisms underlying both conditions.
Regardless of which condition developed first, the combination of PTSD and depression can be particularly difficult. Depression can worsen PTSD symptoms and make recovery more challenging. At the same time, PTSD symptoms like hypervigilance and nightmares can interfere with depression treatment. For these reasons, it’s important that treatment addresses both conditions simultaneously when they co-occur.
Anxiety disorders commonly co-occur with PTSD
The study also found high rates of various anxiety disorders co-occurring with PTSD. The most common was social anxiety disorder, affecting over one-third of those with PTSD. Other anxiety disorders that frequently co-occurred included:
- Obsessive-compulsive disorder (OCD)
- Agoraphobia (fear of places or situations that might cause panic)
- Panic disorder
- Generalized anxiety disorder (GAD)
Like with depression, there is often overlap between anxiety and PTSD symptoms. For example, both conditions can involve heightened alertness to potential threats, avoidance behaviors, and physical symptoms of stress. This can sometimes make it challenging to distinguish where PTSD ends and an anxiety disorder begins.
However, recognizing and addressing co-occurring anxiety disorders is crucial for comprehensive treatment. Specific anxiety disorders may require targeted interventions in addition to PTSD treatment. For instance, exposure therapy techniques used for social anxiety or OCD may need to be carefully integrated with trauma-focused therapies for PTSD.
Substance use disorders are common in PTSD
The study found that about 1 in 10 people with PTSD also struggled with alcohol misuse or dependence. Rates of other substance use disorders were also elevated compared to people without PTSD.
Many people with PTSD report using alcohol or drugs to cope with their symptoms. Substances may temporarily relieve distress or help with sleep problems. However, substance use often backfires in the long run, worsening PTSD symptoms and creating additional problems.
Integrated treatment that addresses both PTSD and substance use simultaneously is generally recommended when these conditions co-occur. This may involve a combination of trauma-focused therapy, addiction treatment approaches, and sometimes medications.
Psychotic symptoms can occur alongside PTSD
One surprising finding from the study was that over 30% of people with PTSD reported experiencing psychotic symptoms. Psychotic symptoms can include hallucinations (seeing or hearing things that others don’t) or delusions (fixed false beliefs).
There are a few potential explanations for this finding:
Some PTSD symptoms, like flashbacks or hypervigilance, can sometimes resemble psychotic experiences.
Severe PTSD may occasionally involve brief psychotic episodes related to the trauma.
The stress of PTSD may trigger psychotic symptoms in vulnerable individuals.
PTSD and psychotic disorders like schizophrenia may sometimes co-occur by chance.
Substance use, which is common in PTSD, can sometimes induce psychotic symptoms.
More research is needed to better understand the relationship between PTSD and psychotic symptoms. However, this finding highlights the importance of thorough assessment, as psychotic symptoms may require specific treatment approaches.
Implications for diagnosis and treatment
The high rates of co-occurring conditions found in this study have several important implications:
Comprehensive assessment is crucial. Clinicians should screen for a range of mental health conditions when evaluating someone with PTSD symptoms.
Treatment may need to address multiple conditions. Focusing solely on PTSD while ignoring co-occurring depression or anxiety, for instance, is likely to be less effective.
Symptoms may overlap between conditions. Careful assessment is needed to tease apart which symptoms are related to PTSD versus other co-occurring disorders.
The presence of certain co-occurring conditions may influence treatment choices. For example, the combination of PTSD and bipolar disorder requires careful medication management.
Recovery may take longer when multiple conditions are present. Patients and providers should set realistic expectations for improvement.
Limitations and future directions
While this study provides valuable insights into patterns of co-occurring conditions in PTSD, there are some limitations to keep in mind:
The data is cross-sectional, meaning it was collected at a single point in time. This makes it impossible to determine which condition developed first or how the relationships between conditions may change over time.
The study relied on self-reported symptoms rather than clinical interviews for some diagnoses.
Cultural factors may influence how mental health conditions manifest and are reported, so findings may not generalize to all populations.
Future research using longitudinal designs (following people over time) could help clarify how different conditions influence each other. Additionally, studies examining biological markers and brain imaging might shed light on shared mechanisms underlying these co-occurring conditions.
Conclusions
Co-occurring mental health conditions are very common in people with PTSD, affecting nearly 80% of those with the disorder.
Depression is the most frequent co-occurring condition, followed by various anxiety disorders.
Substance use disorders and psychotic symptoms also occur at higher rates in people with PTSD.
Recognizing and addressing co-occurring conditions is crucial for comprehensive PTSD treatment.
More research is needed to understand the complex relationships between PTSD and other mental health conditions.
Understanding these patterns of co-occurring conditions can help improve diagnosis and treatment for people struggling with PTSD. By addressing the full range of mental health challenges a person faces, treatment outcomes are likely to be better. If you or someone you know is dealing with PTSD, be sure to discuss any additional symptoms or concerns with a mental health professional to ensure comprehensive care.